This dataset was used to analyse the hydrodynamic effects of floodgate closures in the Venice Lagoon under different management scenarios, namely: - MoSE: The real-case scenario with actual floodgate activations - OPEN: A hypothetical unregulated scenario with no floodgate interventions - AThOS: A hypothetical regulated scenario based on alternative operational strategies Folder: 01_WaterLevels -> Folder - Lagoonal Water Levels Contains .mat files with modelled water levels within the Venice Lagoon during floodgate closures between 2020 and 2023, for the OPEN, MoSE, and AThOS scenarios. Read_WaterLevels.mat: script to generate visualizations of the water level data -> Folder - Venice vs Marsh Flooding Contains .mat files with Venice and salt marsh flooding extend during the 69 floodgates activation under the OPEN, MoSE, and AThOS scenarios. Read_Flood_Extent.mat: script to generate visualizations of the data Folder: 02_Maps Contains .asc and .tiff maps and .mat of salt marsh Mean Inundation Depth (MID) and Sedimentation calculated in for the OPEN, MoSE, and AThOS scenarios. Read_MID.mat and Read_Sedimentation.mat: scripts to generate corresponding visualizations. File: Supplementary.xlsx Contains additional information on model performance, records of floodgate closures, maximum water levels in the major urban settlements, urban flooding, and records of predicted maxima vs observerved water levels in Punta della Salute, Venice, during floodgate closures.