Ceccato, Filippo and Crimì, Filippo (2026) Detection of GLAS in BMAD patients with ARMC5 pathogenic variants. [Data Collection]
Collection description
Background: Bilateral macronodular adrenal disease (BMAD) is a rare disorder characterized by bilateral benign macronodules and variable degrees of hypercortisolism. Pathogenic variants in ARMC5 and KDM1A represent the best-established genetic etiologies. However, it remains uncertain whether quantitative/qualitative CT evaluation characterizes genetically mutated patients. Purpose: To evaluate CT morphological and dimensional differences in BMAD patients with and without ARMC5 pathogenic variants. Materials and Methods: Retrospective single-center study of 101 genetically characterized BMAD patients (66 women; median age, 63 years). CT scans were independently analyzed by three reader teams blinded to clinical/genetic data. Genetic testing was used as reference standard for statistics.
| DOI: |  10.25430/researchdata.cab.unipd.it.00001923 |
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| Keywords: | cushing's syndrome; grape-like adrenal sign | |||||||||
| Subjects: | Life Sciences > Physiology, Pathophysiology and Endocrinology: Organ physiology, pathophysiology, endocrinology, metabolism, ageing, tumorigenesis, cardiovascular diseases, metabolic syndromes > Organ physiology and pathophysiology | |||||||||
| Department: | Departments > Dipartimento di Medicina (DIMED) | |||||||||
| Depositing User: | Filippo Ceccato | |||||||||
| Date Deposited: | 18 Sep 2026 10:54 | |||||||||
| Last Modified: | 18 Sep 2026 10:54 | |||||||||
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| Type of data: | Text | |||||||||
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| Resource language: | english | |||||||||
| Metadata language: | english | |||||||||
| Publisher: | Research Data Unipd | |||||||||
| Date: | 18 September 2026 | |||||||||
| Copyright holders: | The Author | |||||||||
| URI: | https://researchdata.cab.unipd.it/id/eprint/1923 |
orcid.org/0000-0003-1456-8716
